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4-(Aminosulfonyl)-N-[(2,4-Difluorophenyl)Methyl]-Benzamide

Development stage: Unknown
Modality: Small Molecules

Overview

4-(Aminosulfonyl)-N-[(2,4-Difluorophenyl)Methyl]-Benzamide is an experimental small molecule compound containing a benzamide moiety N-linked to a (2,4-difluorophenyl)methyl group. It has been studied primarily as an inhibitor of human carbonic anhydrase II. Structural and binding studies show it binds with high affinity (Kd ~3.3 nM) to the enzyme's active site and interacts via its fluoroaromatic rings[1][2][3]. The compound has not been approved for any indication and is not in clinical development beyond preclinical or structural biology research.

Targets

CA2 (Carbonic Anhydrase 2)

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